Over time, tests have been conducted on Vitadylan™, its ingredients, production procedure, raw materials, and final products by several institutes to guarantee their effect and healthy impact on the skin. We and our partners have made significant investments to ensure that the mixture is the best-possible and cares for the skin perfectly.
Vitadylan™ is not a medical product, but we nonetheless apply the highest standards and collaborate with top-name institutes to prove its quality. We are very proud of these scientific partnerships and would like to extend our heartfelt thanks to our partners for their diligent cooperation with our team in order to make the best imaginable material.
It could be shown that the textile Vitadylan has a direct cytotoxic effect on human HaCaT keratinocytes in vitro. HaCaT cells challenged with doses ≥ 0.1 g:mL died over an incubation period of 24 hours. Extraction ratios of 0.05 and 0.02 g:mL decreased cell proliferation significantly over time in this test. Only the concentration of 0.002 g:mL was well tolerated by the HaCaT cells during the incubation period of 48 hours. Results obtained for 24-hour and 72- hour extracts were found to be similar. However, it could be demonstrated that the textile Vitadylan exhibits a strong antibacterial activity against Staphylococcus aureus and Klebsiella pneumonia according to JIS L 1902:2008 (log-reduction > 3). Furthermore, Vitadylan was found to be able to inhibit the formation of free radicals such as ROS (reactive oxygen species) and RNS (reactive nitrogen species) in vitro. The textile showed a significant, dose-dependent antioxidative capacity against ROS and RNS which probably can be attributed to the vitamins A, C, and E detected in the textile Vitadylan.
|Staphylococcus aureus||Klebsiella pneumoniae|
|strong (75.8% inhibition)||strong (65.0% inhibition)|
1) Klebsiella pneumoniae is a quadruple multidrug-resistant germ, meaning that it is resistant to all four classes of antibiotics and to all 26 antibiotics approved in the United States. He was discovered in five patients at the Frankfurt University Hospital, three of them died. Experts are worried (Die Welt, 6th May, 2017).
2) Infection with Staphylococcus aureus, threaten life-threatening pneumonia or blood poisoning. Clinicians fear the nasty pathogen (Focus Magazine).
The vitamins A, C, and E were detected in the Vitadylan sample material (table 2). It can be assumed that the amounts of vitamin C and E found in the textile are responsible for the good antioxidative capacity observed.
According to the analytical results the tested sample does not contain any amines which can be released from banned azo colourants regulated according to REACH Annex XVII.
There is a strong antibacterial activity with the odour causing test strains Staphylococcus epidermidis ATCC 14990 and Corynebacterium jeikeium ATCC 43734 under given test conditions for the tested samples, calculated with the control material (non treated PES)
On behalf of the United States Department of Agriculture's (USDA's) BioPreferred® program, I am pleased to inform you that your application for use of the USDA Certified Biobased Product Label has been approved as of July 30, 2017. The test result indicates that its biobased content is 100%.
The skin is the major interface between body and environment. It is the most versatile human organ and plays a key role in protecting the body against environmental influences and participates in the regulation of homeostasis, metabolic processes as well as immunological reactions. Oxidative stress by free radicals accelerates skin aging and has been implicated in dermatological diseases such as atopic dermatitis. UV light induces the generation of free radicals in the cells; hence, the application of topical antioxidants has been recommended. Textiles are the tissues with the longest contact to the human skin. In the clinically and cosmetically field they are used manifold; one scope of application is for instance the functionalization of fabrics with antioxidants.
The textile samples (1508G15-1, 1508G15-2 and 1508G15-3) exhibited significant, concentration-dependent capacity to inhibit the formation of free reactive oxygen species (Figure 1). Furthermore, the textile samples (1508G15-1, 1508G15-2 and 1508G15-3) were able to reduce the formation of reactive nitrogen species (Figure 2). In accordance, significant difference between the textile samples (1508G15-1, 1508G15-2 and 1508G15-3) and the control group were observed (p < 0.001).
91 % DPPH free radicals removing rate
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